Flash Technology-Based Self-Assembly in Nanoformulation: From Fabrication to Biomedical Applications
Hanze Hu1, Chao Yang1,2, Mingqiang Li3
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Materials Today (Kidlington, England)
|August 23, 2021
Summary
Flash-based technology revolutionizes nanomedicine by enabling rapid self-assembly of macromolecules for biosensing, imaging, and drug delivery. This review covers flash nanocomplexation (FNC) and flash nanoprecipitation (FNP) for advanced biomedical applications.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Materials Science
Background:
- Nanoformulation advances enable nanoscale tools for biosensing, imaging, and drug delivery.
- Flash-based technology combines rapid mixing with macromolecule self-assembly for translational nanomedicine.
Purpose of the Study:
- To review the state-of-the-art in flash-based self-assembly techniques.
- To highlight flash nanocomplexation (FNC) and flash nanoprecipitation (FNP) in biomedicine.
- To discuss challenges and future directions in flash-based nanoformulation.
Main Methods:
- Review of theoretical and experimental principles of flash-based self-assembly.
- Analysis of mixing device designs for flash-based nanoformulation.
- Focus on biomedical applications, particularly FNC.
Main Results:
- Flash-based self-assembly offers a novel approach for creating nanoscale tools.
- FNC and FNP are key techniques within flash-based nanoformulation.
- Significant potential exists for FNC in biomedical applications.
Conclusions:
- Flash-based technology is a powerful engine for translational nanomedicine.
- Further research into FNC and FNP can accelerate biomedical advancements.
- Addressing challenges in flash-based nanoformulation will unlock future potential.
