Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neurulation

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...

Uterus and Cervix

Uterus and Cervix

The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs...

Uterine Tubes

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A multi-center retrospective study comparing one-step nucleic amplification and conventional ultrastaging for sentinel lymph node assessment in early-stage endometrial cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026

Same author

Lymphovascular Space Invasion in Early-Stage Endometrial Cancer (LySEC): Patterns of Recurrence and Predictors. A Multicentre Retrospective Cohort Study of the Spain Gynecologic Oncology Group.

Cancers·2023

Same author

First-Trimester Sequential Screening for Preeclampsia Using Angiogenic Factors: Study Protocol for a Prospective, Multicenter, Real Clinical Setting Study.

Frontiers in cardiovascular medicine·2022

Same author

Chylous Ascites Secondary to Retroperitoneal Para-Aortic Lymphadenectomy: A Case Report.

Cureus·2022

Same author

Lower-Limb Lymphedema after Sentinel Lymph Node Biopsy in Cervical Cancer Patients.

Cancers·2021

Same author

Rotational forceps: a retrospective study evaluating anatomical and functional consequences for the pelvic floor.

International urogynecology journal·2021

Search research articles

Related Experiment Video

Updated: Oct 23, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Uterine Primitive Neuroectodermal Tumor.

Taysa Benitez Delgado¹, Maria Laseca-Modrego¹, Daniel Gonzalez Garcia-Cano¹

¹Gynecologic Oncology, Complejo Hospitalario Universitario (C.H.U.) Insular-Materno Infantil, Las Palmas de Gran Canaria, ESP.

|August 23, 2021

Summary

Uterine primitive neuroectodermal tumors (PNETs) are rare and aggressive cancers. This case highlights a PNET diagnosis in an elderly patient, emphasizing the need for better treatment strategies and survival data.

Keywords:

ewing gynecology neuroectodermal oncology primitive prognosis sarcoma tumor uterus

More Related Videos

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

Published on: August 25, 2021

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Related Experiment Videos

Last Updated: Oct 23, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

Published on: August 25, 2021

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Area of Science:

Gynecologic Oncology
Pathology
Oncology

Background:

Uterine primitive neuroectodermal tumors (PNETs) are exceptionally rare gynecologic malignancies.
They are characterized by aggressive behavior and a poor prognosis, often diagnosed at advanced stages.

Observation:

A case report of a 71-year-old postmenopausal woman presenting with metrorrhagia and endometrial thickening.
Pathological diagnosis confirmed PNET via endometrial biopsy.
Staging revealed distant dissemination, including sigmoid and liver infiltration.

Findings:

The patient's disease progressed rapidly, precluding chemotherapy initiation.
Death occurred due to multiple organ failure within four months of diagnosis.
Current chemotherapy regimens lack established efficacy for uterine PNET.

Implications:

There is a critical need for further research into uterine PNET treatment protocols.
Increased focus on patient follow-up and survival data is essential.
Establishing optimal therapeutic strategies is crucial to improve the dismal prognosis of uterine PNET.