Related Experiment Video
Updated: Oct 23, 2025

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
Dry Eye Symptoms in Individuals With Keratoconus Wearing Contact Lenses
Ellen Shorter1, Jennifer Harthan, Amy Nau
1Department of Ophthalmology and Visual Sciences (E.S., D.C.), University of Illinois at Chicago, Chicago, IL; Cornea Center for Clinical Excellence (J.H.), Illinois College of Optometry, Chicago, IL; Korb & Associates (A.N.), Boston, MA; College of Optometry (J.F.), Ohio State University College of Optometry, Columbus, OH; and Mayo Clinic (M.S., C.N.), Rochester, MN.
Objectives:
To assess dry eye symptoms associated with different contact lens modalities in patients with keratoconus using a dry eye questionnaire.
Methods:
An online survey was distributed by the National Keratoconus Foundation. The survey asked participants to report demographic characteristics, current optical correction, age at the time of diagnosis of keratoconus, and contact lens history. The 12-item Ocular Surface Disease Index (OSDI) questionnaire was also completed. Data from participants wearing the same contact lens modality bilaterally were analyzed.
Results:
The survey was completed by 197 individuals wearing the same contact lens modality bilaterally. The average age of participants at the time of the survey was 47.2±14.8 years (range: 15-87 years), and the average age at which keratoconus was diagnosed was 26.1±9.9 years (range: 8-55 years). The mean overall OSDI score of all participants was 40.2±22.8 (range: 0-100). There was no difference in the mean OSDI scores based on current contact lens modality type (F=1.79; n=187; P=0.13). Based on an OSDI score of 33 or higher, 90% of participants reported symptoms indicative of dry eye disease. Scleral lens wearers reported less discomfort on the individual items related to windy and low-humidity conditions.
Conclusions:
Individuals with keratoconus, irrespective of contact lens modality, report a high incidence of dry eye symptoms.
More Related Videos
Related Concept Videos
Accessory Structures of the Eye
Glaucoma: Overview
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Focusing of Light in the Eye
Photoreceptors and Visual Pathways

