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Related Concept Videos

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3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
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3D printing fluorescent material with tunable optical properties.

Alberto J Ruiz1,2, Sadhya Garg3, Samuel S Streeter3

  • 1Thayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA. albertojruiz.ar@gmail.com.

Scientific Reports
|August 25, 2021
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel 3D printing method for fluorescent materials, enabling precise control over optical properties. This advancement supports the creation of advanced imaging technologies, including fluorescence-guided surgery systems.

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Area of Science:

  • Biomedical Optics
  • Materials Science
  • Additive Manufacturing

Background:

  • 3D printing of fluorescent materials is crucial for developing advanced imaging technologies like fluorescence-guided surgery.
  • Existing methods lack comprehensive approaches for simultaneous fluorophore incorporation and optical property tuning.

Purpose of the Study:

  • To introduce a photopolymer-based 3D printing method for manufacturing fluorescent materials with tunable optical properties.
  • To demonstrate the simultaneous incorporation of various fluorophores and fine-tuning of absorption and scattering coefficients.

Main Methods:

  • Utilized a photopolymer-based 3D printing technique.
  • Incorporated individual fluorophores such as IR-125, quantum dots, methylene blue, and rhodamine 590.
  • Tuned absorption and reduced scattering coefficients to mimic mammalian soft tissue optical properties.

Main Results:

  • Achieved reasonably high fluorescence yields for printed individual fluorophores.
  • Demonstrated tuning of absorption coefficients (0.005-0.05 mm⁻¹) and reduced scattering coefficients (0.2-1.5 mm⁻¹).
  • Successfully fabricated complex geometric structures with feature sizes below 200 μm.

Conclusions:

  • The developed 3D printing method enables the creation of solid fluorescent structures with tailored optical properties.
  • This technology provides a foundation for manufacturing advanced materials for biomedical optics and fluorescence imaging.
  • Facilitates the broad adoption of rapid manufacturing in fluorescence imaging applications.