Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is hypertension treated adequately?

L Hansson1, J I Robertson

  • 1Department of Medicine, University of Göteborg, Ostra Hospital.

Drugs
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparison and an investigation of a potential synergistic effect of labetalol and bethanidine in patients with mild hypertension.

British journal of clinical pharmacology·2015
Same author

Treatment of severe hypertension by repeated bolus injections of labetalol.

British journal of clinical pharmacology·2015
Same author

Plasma Renin Concentration in Human Hypertension-III: Renin in Relation to Complications of Hypertension.

British medical journal·2010
Same author

Plasma Renin Concentration in Human Hypertension. IV: Renin in Relation to Treatment and Prognosis.

British medical journal·2010
Same author

The renin-angiotensin system in the twenty-first century.

Blood pressure·2002
Same author

Cautions over idiopathic aldosteronism.

Lancet (London, England)·2001
Same journal

The Long Road to Long-Acting: What Oral PrEP and CAB-LA Teach Us About Scaling Lenacapavir.

Drugs·2026
Same journal

Botulinum Toxin Type A for Trigeminal and Postherpetic Neuralgia: An Umbrella Review of Systematic Reviews.

Drugs·2026
Same journal

Biologics and Small Molecule Inhibitors: Novel Therapeutic Strategies for Cutaneous Adverse Drug Reactions.

Drugs·2026
Same journal

Use of Sedative-Hypnotic Drugs and the Risk of Developing Alzheimer's Disease: A Systematic Review, Meta-Analysis and Meta-Regression.

Drugs·2026
Same journal

Relacorilant: First Approval.

Drugs·2026
Same journal

Developmental Progress and Future Potential for Inhaled Biologics in the Treatment of Respiratory Diseases.

Drugs·2026
See all related articles

Despite blood pressure control, treated hypertensive patients face high morbidity and mortality. This suggests irreversible changes or adverse drug effects may persist, impacting long-term cardiovascular health.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Pharmacology

Background:

  • Blood pressure levels strongly correlate with morbidity and mortality in hypertensive patients.
  • Antihypertensive treatment demonstrates a relationship between treated blood pressure and patient prognosis.
  • Recent studies reveal elevated morbidity and mortality in treated hypertensive individuals compared to normotensive populations.

Purpose of the Study:

  • To investigate the reasons behind persistent high morbidity and mortality in treated hypertensive patients.
  • To explore potential explanations for suboptimal outcomes despite blood pressure management.

Main Methods:

  • Analysis of findings from three large-scale studies on treated hypertensive patients.
  • Review of potential contributing factors including irreversible cardiovascular changes, adverse drug effects, and suboptimal blood pressure control.

Related Experiment Videos

Main Results:

  • Treated hypertensive patients exhibit higher than expected morbidity and mortality rates.
  • Long-standing hypertension may lead to irreversible cardiovascular damage.
  • Pharmacological treatments might have adverse effects (e.g., on lipids, electrolytes) counteracting benefits.
  • Consistent blood pressure reduction is achieved in only a fraction of treated patients.

Conclusions:

  • Persistent cardiovascular risks in treated hypertensive patients warrant further investigation.
  • Adverse effects of antihypertensive medications and incomplete blood pressure control are potential factors.
  • Understanding these factors is crucial for improving long-term outcomes in hypertension management.