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Bilateral Fungus Ball: An Uncommon Complication Post Severe COVID 19 Infection

Yash S Kedia1, N T Awad2, Jairaj P Nair3

  • 1Resident Doctor, Department of Respiratory Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra;Corresponding Author.

The Journal of the Association of Physicians of India
|August 25, 2021
PubMed

Insights

This case report details a rare complication following severe COVID-19 pneumonia. A patient developed bilateral lung cavities and a fungus ball, a previously undocumented sequela of SARS-CoV-2 infection.

Area of Science:

  • Medicine
  • Infectious Diseases
  • Pulmonology

Background:

  • COVID-19, caused by SARS-CoV-2, is a global pandemic primarily affecting the respiratory system.
  • Severe cases can lead to Acute Respiratory Distress Syndrome (ARDS) and subsequent bilateral lung fibrosis.
  • Secondary infections are known complications of severe COVID-19 pneumonia.

Observation:

  • A case report of a patient with ARDS due to SARS-CoV-2 infection is presented.
  • The patient required non-invasive ventilation (NIV) and home oxygen post-discharge.
  • Initial HRCT showed bilateral lung fibrosis, a known post-COVID-19 sequela.

Findings:

  • A follow-up HRCT, 45 days after discharge, revealed the development of bilateral cavities.
  • The imaging also showed evidence of a fungus ball within these cavities.
  • This combination of fibrocavitation and fungus ball represents a novel post-COVID-19 complication.

Implications:

  • This finding expands the spectrum of known pulmonary complications following severe COVID-19.
  • It highlights the potential for unusual fungal superinfections in patients with post-COVID-19 lung damage.
  • Further research is needed to understand the pathogenesis and management of these rare sequelae.

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