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Integrative neurovegetative and motor control: phenomena and theory
H P Koepchen1, H H Abel, D Klüssendorf
1Institute of Physiology, Free University of Berlin, Federal Republic of Germany.
Functional Neurology
|October 1, 1987
Summary
Central control systems for bodily functions like circulation and respiration are not entirely separate. A multifunctional neural network underlies common central rhythmicity, where neuronal specificity is quantitative and increases towards outputs.
Area of Science:
- Neuroscience
- Systems Biology
- Physiology
Background:
- Investigates the specificity of central control systems for peripheral functions.
- Examines the control of circulation, respiration, and motor innervation.
- Addresses the existence of separate central control systems.
Purpose of the Study:
- To analyze the coordination of rhythmic activities in biological systems.
- To determine the nature of central control mechanisms.
- To propose a model for multifunctional neural networks.
Main Methods:
- Analysis of experimental studies on spontaneous rhythmic activities in anesthetized dogs and conscious humans.
- Microelectrode recordings and local cooling experiments in the brain stem of anesthetized dogs and cats.
- Logical deduction and model outlining.
Main Results:
- Central control systems are partly identical, not entirely separate.
- Neuronal specificity is a quantitative property within a multifunctional common network.
- The degree of neuronal specificity increases towards the outputs.
Conclusions:
- A common multifunctional network forms the substrate for central rhythmicity.
- Specificity is a quantitative, condition-dependent property of neurons.
- The proposed network model explains observed phenomena in animal experiments.