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[Central hemodynamic function of neurocirculatory dystonia patients at rest and during the performance of load tests]
Insights
Neurocirculatory dystonia (NCD) patients showed inadequate hemodynamic responses to stress. Severe NCD with hyperkinetic type exhibited insufficient minute volume rise and stroke index decline during exertion.
Area of Science:
- Cardiology
- Physiology
- Clinical Medicine
Background:
- Neurocirculatory dystonia (NCD) is a condition affecting central hemodynamic (CH) parameters.
- Understanding the hemodynamic profile of NCD during physiological stress is crucial for diagnosis and management.
Purpose of the Study:
- To investigate central hemodynamic parameters in patients with neurocirculatory dystonia (NCD) compared to normal subjects.
- To assess the hemodynamic response to various stress tests in NCD patients.
Main Methods:
- Radiocardiography (RCG), echocardiography (EchoCG), and thermodilution (TD) were employed.
- Measurements were taken at rest and during bicycle ergometry (BEM), atrial stimulation test (AST), and intravenous isadrin test (IT).
- 288 NCD patients and 50 healthy controls participated.
Main Results:
- Patients with severe NCD and a hyperkinetic hemodynamic type showed an inadequate increase in minute volume (MV) and a decrease in stroke index (SI) under stress.
- Thermodilution during AST revealed elevated MV, reduced end-diastolic left-ventricular pressure, and a non-significant reduction in SI.
- TD and EchoCG yielded comparable results during stress.
Conclusions:
- Severe NCD, particularly the hyperkinetic type, is characterized by impaired hemodynamic adaptation to stress.
- The findings highlight specific CH parameter alterations in NCD patients during physiological challenges.
- RCG, EchoCG, and TD are valuable tools for assessing hemodynamic function in NCD.
Abstract:
Central hemodynamic (CH) parameters were examined in 288 patients with neurocirculatory dystonia (NCD) and 50 normal subjects, using radiocardiography (RCG), echocardiography (EchoCG) and heart catheterization thermodilution (TD). All the tests were carried out at rest and during bicycle ergometry (BEM), the atrial stimulation test (AST) and the intravenous isadrin test (IT). Patients with severe NCD and basically hyperkinetic hemodynamic type responded to stress with an inadequate rise in the minute volume (MV) and a decline of the stroke index (SI). Thermodilution during the AST demonstrated increased MV, lowered end diastolic left-ventricular pressure and insignificantly reduced SI. TD and EchoCG during stress exposure produced similar results.