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Published on: December 18, 2013
Evaluation of Preoperative Salivary Cortisol Level in Patients Undergoing Major Maxillofacial Surgery
Archana Kumari1, Praveen Chandra2, Sonali Roy3
1Department of Dentistry, VIMS Pawapuri (Nalanda), Patna, Bihar, India.
Aim:
The main purpose of the study was to compare the preoperative salivary cortisol levels 3 days before the major surgery under general anesthesia and to compare it with the patients undergoing extraction under local anesthesia.
Materials And Methods:
Forty-two patients were undergoing major surgery and 42 age- and sex-matched patients undergoing dental extraction were included and their salivary cortisol levels were analyzed before and after the dental procedure.
Results:
Results showed that there is a significant increase in the mean salivary cortisol concentration after extraction (23.7 ± 9.2) than before extraction (18.9 ± 23.7) in the study group (P = 0.015) as well as in the control group. The comparison between salivary cortisol in the study group before (18.9 ± 23.7) and after (23.7 ± 9.2) surgery was significantly higher than the control group (15.2 ± 5.5) (P = 0.013 and 0.005), respectively.
Conclusion:
We have concluded from this study that the salivary cortisol level shows a significant increase on the day of surgery.
