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Sclerotherapy as an alternative treatment for complex, refractory seromas
Nicole C Episalla1, Susan Orra1, Cara K Black2
1Department of Plastic and Reconstructive Surgery, Medstar Georgetown University Hospital, Washington, DC 20007, USA.
Journal of Surgical Case Reports
|August 27, 2021
Summary
Sclerotherapy offers a promising treatment for complex, persistent seromas that resist traditional therapies. This interventional radiology technique effectively resolved chronic, high-volume seromas in a case series.
Area of Science:
- Interventional Radiology
- Surgical Oncology
- Regenerative Medicine
Background:
- Traditional seroma management includes compression, aspiration, drainage, or surgery.
- Complex, treatment-refractory seromas pose a significant clinical challenge.
- Limited evidence exists for sclerotherapy in complex, post-operative seromas.
Observation:
- A case series explored sclerotherapy using interventional radiology for chronic, high-volume post-operative seromas.
- Patients had complex medical histories and failed multiple traditional treatments.
- Sclerotherapy was used as an alternative or adjunctive treatment.
Findings:
- Seromas resolved after a maximum of four sclerotherapy rounds.
- Various combinations of sclerosants were utilized.
- Long-term follow-up confirmed resolution.
Implications:
- Sclerotherapy is a viable alternative for recalcitrant post-operative seromas.
- Interventional radiology offers effective management for complex seroma cases.
- This approach may reduce the need for repeated surgical interventions.

