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Updated: Oct 22, 2025

Investigating Migraine-Like Behavior Using Light Aversion in Mice
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Current Perspective on Retinal Migraine.

Yu Jeat Chong1, Susan P Mollan1, Abison Logeswaran2

  • 1Birmingham Neuro-Ophthalmology, Ophthalmology Department, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.

Vision (Basel, Switzerland)
|August 27, 2021
PubMed
Summary
This summary is machine-generated.

Retinal migraine, a rare condition causing temporary monocular visual disturbances, requires careful diagnosis. Its definition and underlying mechanisms remain debated, necessitating further research.

Keywords:
migraine auraocular migraineophthalmic migraineretinal migraine

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Area of Science:

  • Neurology
  • Ophthalmology

Background:

  • Retinal migraine has been described since 1882, with inconsistent terminology like "ocular migraine" causing confusion.
  • The International Classification of Headache Disorders (ICHD) defines it as reversible monocular visual disturbances with migraine headache.
  • Current understanding suggests its proposed etiology may differ from typical migraine mechanisms.

Purpose of the Study:

  • To review the existing literature on retinal migraine.
  • To summarize epidemiology, risk factors, etiology, clinical presentation, and management.

Main Methods:

  • This is a narrative review of the literature on retinal migraine.

Main Results:

  • Retinal migraine, as defined by ICHD, is rare.
  • It is a diagnosis of exclusion, requiring other causes of transient monocular visual loss to be ruled out.
  • The term "retinal migraine" may be a misnomer due to differing proposed etiologies.

Conclusions:

  • Consistent definitions and understanding of retinal migraine's etiology are needed.
  • Further research is essential for accurate diagnosis and effective management of this rare condition.