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Congenital Bilateral Wilms Tumor: A Case Report
Deguang Meng1, Xiaofeng Chang2, Qinghua Ren2
1Baoding Children's Hospital, Baoding, Hebei, PR China.
Urology
|August 27, 2021
Summary
Congenital bilateral Wilms tumor, extremely rare in fetuses, presents a diagnostic and therapeutic challenge. This case highlights successful management through neoadjuvant chemotherapy, surgical enucleation, and adherence to international pediatric oncology guidelines.
Area of Science:
- Pediatric Oncology
- Fetal Medicine
- Nephropathology
Background:
- Congenital Wilms tumor is exceptionally rare compared to fetal congenital mesoblastic nephroma.
- Early detection and accurate diagnosis are crucial for effective management of rare pediatric renal tumors.
Observation:
- A case involving congenital bilateral solid renal masses detected via antenatal ultrasound.
- Postnatal evaluation included ultrasonography and contrast-enhanced computed tomography.
- The patient received neoadjuvant chemotherapy prior to surgical intervention.
Findings:
- Histological analysis confirmed the diagnosis of bilateral Wilms tumor.
- Tumor enucleation was performed sequentially for each affected kidney.
- Treatment followed protocols established by the International Society of Pediatric Oncology.
Implications:
- This case underscores the importance of advanced imaging in diagnosing rare fetal renal masses.
- Successful application of neoadjuvant chemotherapy followed by surgical management offers a potential therapeutic strategy.
- Adherence to international guidelines is vital for optimizing outcomes in congenital Wilms tumor cases.
