Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

Viral Meningitis

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

Arboviral Encephalitis

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...

Toxoplasmosis

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

Encephalitis l: Introduction

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

Encephalitis ll: Pathophysiology

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Persistent placoid maculopathy: long term outcomes and prognostic factors.

Retina (Philadelphia, Pa.)·2026

Same author

Retinal vascular occlusions during COVID-19: an epidemiological survey.

Frontiers in ophthalmology·2026

Same author

UveAI: clinic-ready scoring of retinal inflammation in uveitis on widefield fluorescein angiography using AI.

Scientific reports·2026

Same author

[Infratentorial superficial siderosis : a diagnostic challenge from the general practice to the hospital].

Revue medicale suisse·2026

Same author

Are the SUN Criteria Sufficient for Tubercular Uveitis? Findings From a Multinational Registry Study.

Investigative ophthalmology & visual science·2026

Same author

A case of paracentral acute middle maculopathy and retinal vein occlusion: idiopathic occlusive retinal vasculitis or incomplete Behçet's disease?

BMC ophthalmology·2025

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Tick-borne encephalitis related uveitis: a case report.

Nafsika Voulgari¹, Claire-May Blanc², Vanessa Guido³

¹Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, avenue de France 15, 1002, Lausanne, Switzerland.

BMC Ophthalmology

|August 29, 2021

Summary

This summary is machine-generated.

This study reports a new association between Tick-Borne Encephalitis Virus (TBEV) and uveitis, a rare eye inflammation. Prompt recognition and treatment of TBEV infection are crucial for preventing severe neurological and ocular complications.

Keywords:

Case report Infectious disease Infectious uveitis Tick-born encephalitis Uveitis Viral uveitis Virus

More Related Videos

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Related Experiment Videos

Last Updated: Jun 26, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Area of Science:

Neuroscience
Ophthalmology
Infectious Diseases

Background:

Tick-borne encephalitis (TBE) is a growing concern in Europe and Asia, caused by the TBE virus (TBEV).
Ocular involvement in TBE has not been previously documented in medical literature.
TBEV is transmitted via tick bites and affects the central nervous system.

Observation:

A patient presented with neurological symptoms including headache and ataxia following a tick bite.
The patient subsequently developed unilateral visual loss and was diagnosed with non-granulomatous anterior uveitis with retinal hemorrhages.
Cerebrospinal fluid PCR was negative for herpes viruses, and initial serology for Borreliosis and TBEV was negative.

Findings:

TBEV seroconversion confirmed the diagnosis of TBE.
The patient's uveitis and neurological symptoms resolved completely with supportive care.
This case establishes a novel association between TBEV and uveitis.

Implications:

This finding expands the known clinical spectrum of TBEV infection.
Increased awareness of TBEV-related uveitis is crucial for early diagnosis and management.
Prompt recognition and treatment can prevent long-term visual or neurological sequelae.