[The intrathecal infusion test in the study of craniospinal cerebrospinal fluid dynamics. A new assessment procedure]

A new mathematical method is presented for calculation of cerebrospinal fluid (CSF) parameters. Intrathecal lumbal infusion test with constant flow technique was used. Resistance to CSF outflow R(p) and compliance C(p) are computed by continuous comparing the change of pressure response dp/dt during infusion and--dp/dt after infusion. Using of this method, it is not necessary to determine the pressure plateau at the steady-state between artificial volume loading and the rate of CSF outflow. With that we were able to minimize the physical load on the patient. The expressiveness of investigation is increased by printing graphs of pressure-dependent resistance CSF outflow and compliance.