PEG-coated patch parenchymal closure technique and initial outcomes during minimally invasive partial nephrectomy.

Area of Science:

• Urology
• Surgical Innovation
• Medical Devices

Background:

• The Hemopatch® is a novel topical hemostatic agent utilizing a polyethylene glycol-coated (PEG-coated) collagen patch.
• It has been applied across various surgical procedures.
• This study focuses on its application in minimally invasive partial nephrectomy (MIPN).

Purpose of the Study:

• To present a series and technique using a PEG-coated patch for MIPN.
• To evaluate the safety and efficacy of this hemostatic agent in renal surgery.

Main Methods:

• A retrospective chart review of 17 patients undergoing MIPN between July and December 2018.
• Inclusion criteria required the use of a PEG-coated patch for renal parenchymal defect closure.
• The study details the laparoscopic patch deployment technique.

Main Results:

• Seventeen patients met inclusion criteria; 12 were male, with a mean age of 63.
• Median renal mass size was 2.85 cm; median RENAL score was 6.
• Average warm ischemic time was 16.1 minutes for 12 cases with hilar clamping. Median estimated blood loss was 238 mL, with no transfusions, angioembolization, or re-operations for bleeding within 90 days. No Clavien-Dindo grade 3+ complications occurred.

Conclusions:

• A PEG-coated patch serves as a safe and effective alternative to traditional two-layer renorrhaphy for MIPN.
• Acceptable outcomes were observed, but larger prospective studies are needed to confirm cost-effectiveness.