Related Experiment Video
Updated: Oct 22, 2025

Trajectory Data Analyses for Pedestrian Space-time Activity Study
Published on: February 25, 2013
On the utility of a well-mixed model for predicting disease transmission on an urban bus
Zhihang Zhang1, Jesse Capecelatro2, Kevin Maki1
1Department of Naval Architecture and Marine Engineering, University of Michigan, Ann Arbor, Michigan 48109-2145, USA.
Abstract:
The transport of virus-laden aerosols from a host to a susceptible person is governed by complex turbulent airflow and physics related to breathing, coughing and sneezing, mechanical and passive ventilation, thermal buoyancy effects, surface deposition, masks, and air filtration. In this paper, we study the infection risk via airborne transmission on an urban bus using unsteady Reynolds-averaged Navier-Stokes equations and a passive-scalar model of the virus-laden aerosol concentration. Results from these simulations are directly compared to the widely used well-mixed model and show significant differences in the concentration field and number of inhaled particles. Specifically, in the limit of low mechanical ventilation rates, the well-mixed model will overpredict the concentration far from the infected passenger and substantially underpredict the concentration near the infected passenger. The results reported herein also apply to other enclosed spaces.
Related Concept Videos
Steps in Outbreak Investigation
Mechanistic Models: Compartment Models in Individual and Population Analysis
Models of Health Promotion and Illness Prevention II
The agent-host-environment model states that disease results...
Models of Health Promotion and Illness Prevention I
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
Causality in Epidemiology
Principles of Disease Surveillance

