Related Experiment Video
Updated: Oct 21, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Comparative Effectiveness of Clinical and Community-Based Approaches to Healthy Weight
Lauren Fiechtner1,2, Meghan Perkins3, Vincent Biggs4
1Division of General Academic Pediatrics, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, Massachusetts lfiechtner@mgh.harvard.edu.
The Healthy Weight Clinic (HWC) effectively reduced BMI in Hispanic children, while the modified Healthy Weight and Your Child (M-HWYC) intervention did not show significant results. HWC offers a promising pediatric weight management solution.
Area of Science:
- Pediatric Endocrinology
- Public Health Nutrition
- Behavioral Medicine
Background:
- Childhood obesity, particularly among low-income Hispanic populations, presents a significant public health challenge.
- Effective, accessible interventions are crucial for managing pediatric weight and preventing associated comorbidities.
- Existing pediatric weight management programs require evaluation for efficacy in diverse, underserved communities.
Purpose of the Study:
- To compare the effectiveness of two pediatric weight management interventions in reducing Body Mass Index (BMI) among Hispanic children.
- To evaluate if a health center-based Healthy Weight Clinic (HWC) is non-inferior to a community-based modified Healthy Weight and Your Child (M-HWYC) program.
- To assess the impact of these interventions on BMI and BMI percentile changes in a low-income pediatric population.
Main Methods:
- A randomized controlled trial involving 407 Hispanic children (aged 6-12 years) with BMI at or above the 85th percentile.
- Interventions included a Healthy Weight Clinic (HWC) at a health center and a modified Healthy Weight and Your Child (M-HWYC) program at a Young Men's Christian Association (YMCA).
- Non-inferiority testing was conducted by comparing the change in %BMIp95 between interventions, with a comparison group of 4037 children used for yearly BMI change analysis.
Main Results:
- The M-HWYC intervention was not found to be non-inferior to the HWC, with a mean difference in %BMIp95 of 0.75 (90% CI: 0.07 to 1.43).
- Children in the HWC showed a statistically significant decrease in BMI (-0.23 per year) and %BMIp95 (-1.03 per year) compared to the comparison sites.
- No significant BMI changes were observed in children participating in the M-HWYC intervention.
Conclusions:
- The modified Healthy Weight and Your Child (M-HWYC) intervention failed to demonstrate non-inferiority to the Healthy Weight Clinic (HWC).
- The HWC intervention proved effective in improving BMI among participating children, suggesting it is a viable treatment option.
- The findings highlight the HWC as an effective strategy for pediatric weight management, particularly for disproportionately affected populations.
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