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Paraneoplastic papilloedema in neuroblastoma
M J Kennedy1, P Eustace, D S O'Briain
1Department of Oncology, St. James's Hospital, Dublin, Republic of Ireland.
Postgraduate Medical Journal
|October 1, 1987
Summary
This study describes bilateral papilloedema in an adult male with neuroblastoma, a rare complication not previously documented in English literature. The findings suggest a potential link between neuroblastoma and this specific visual disturbance.
Area of Science:
- Neuro-oncology
- Ophthalmology
Background:
- Neuroblastoma is a rare cancer primarily affecting children, but can occur in adults.
- Papilloedema, or swelling of the optic disc, is often associated with increased intracranial pressure.
Observation:
- A case of bilateral papilloedema was observed in an adult male patient.
- The patient had a confirmed diagnosis of neuroblastoma.
- No hypertension or intracranial disease was detected in the patient.
Findings:
- This presentation of bilateral papilloedema in an adult with neuroblastoma is novel and not previously reported in the English-speaking medical literature.
- The absence of hypertension and intracranial pathology suggests alternative mechanisms for papilloedema in this context.
Implications:
- This case highlights a potential, previously unrecognized complication of neuroblastoma.
- Further research is warranted to elucidate the underlying mechanisms connecting neuroblastoma and papilloedema.
- Clinicians should consider neuroblastoma in the differential diagnosis of unexplained papilloedema in adults.