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Updated: Oct 21, 2025

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Exercise-Induced Left Bundle Branch Block Resulting in Severe Mitral Regurgitation
Brenden S Ingraham1, Panithaya Chareonthaitawee1, Yogesh N V Reddy1
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Abstract:
Exercise hemodynamic catheterization is helpful to evaluate exertional symptoms when noninvasive investigations fail to provide an explanation in non-ischemic cardiomyopathy. In this case, a rate-related left bundle branch block resulted in severe dynamic mitral regurgitation and acute increase in pulmonary capillary wedge pressure. Cardiac resynchronization therapy resolved her symptoms. (Level of Difficulty: Intermediate.).
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