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Protocol for Testing the Potential Antioxidant Effects of Curcuminoids on Patients with Type 2 Diabetes Mellitus
Tannaz Jamialahmadi1,2, Yunes Panahi3, Muhammed Majeed4
1Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran.
Abstract:
Oxidative stress has a key role in the pathogenesis of type 2 diabetes mellitus. Alternative therapy with antioxidants has been tested as a potential approach to curb the effects of this disorder. Here, we present a protocol to set up a randomized double-blind placebo-controlled trial to assess the impact of treatment with a mixture of curcuminoids on a number of physiological and molecular biomarker measures with the main focus on determining the total antioxidant capacity.
Insights
This study outlines a trial investigating curcuminoids as a treatment for type 2 diabetes. It aims to measure the impact on oxidative stress and total antioxidant capacity.
Area of Science:
- Biochemistry
- Endocrinology
- Clinical Trials
Background:
- Oxidative stress is implicated in the development of type 2 diabetes mellitus.
- Antioxidant therapies are being explored as a strategy to manage diabetes complications.
Purpose of the Study:
- To detail a protocol for a randomized double-blind placebo-controlled trial.
- To evaluate the effects of curcuminoid mixture on biomarkers related to type 2 diabetes.
- To primarily assess the impact on total antioxidant capacity.
Main Methods:
- Protocol for a randomized double-blind placebo-controlled trial.
- Assessment of physiological and molecular biomarkers.
- Focus on measuring total antioxidant capacity.
Main Results:
- N/A - This is a protocol description.
Conclusions:
- N/A - This is a protocol description.
