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A prospective, randomized study of 5-fluorouracil and filtration surgery
J M Ruderman1, D B Welch, M F Smith
1Department of Ophthalmology, Northwestern University Medical School, Chicago, Illinois.
Transactions of the American Ophthalmological Society
|January 1, 1987
Abstract:
Our study shows that use of a small dose of subconjunctival 5-FU provides significantly lower postoperative intraocular pressure than does no antimetabolite treatment. Morphology of the postoperative blebs suggests that increased filtration results in lower intraocular pressure in the 5-FU group. Corneal epithelial defects were as common with a low dose as with higher doses previously described.