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Related Concept Videos

IR Spectrometers01:25

IR Spectrometers

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There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...
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Raman Spectroscopy Instrumentation: Overview01:26

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A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
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Atomic Absorption Spectroscopy: Interference01:25

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Interference leads to systematic error in atomic absorption (AA) measurements by enhancing or diminishing the analytical signal or the background. These interferences can be grouped into three main categories: spectral interference, chemical interference, and physical interference.
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IR Spectrum Peak Splitting: Symmetric vs Asymmetric Vibrations01:08

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Identical bonds within a polyatomic group can stretch symmetrically (in-phase) or asymmetrically (out-of-phase). Similar to hydrogen bonding, these vibrations also influence the shape of the IR peak. Generally, asymmetric stretching frequencies are higher than symmetric stretching frequencies. For example, primary amines exhibit two distinct IR peaks between 3300–3500 cm−1 corresponding to the symmetric and asymmetric N-H stretching, while secondary amines exhibit a single...
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Infrared (IR) Spectroscopy: Overview01:09

Infrared (IR) Spectroscopy: Overview

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When electromagnetic radiation passes through a material, atoms or molecules transition from a lower to a higher energy state by absorbing radiation corresponding to the energy difference between the two states. The absorption of infrared (IR) radiation causes transitions between vibrational energy levels in a molecule. Therefore, IR spectroscopy is a useful analytical tool for determining the molecular structure of molecules.
Different compounds display unique properties due to their...
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Wideband Optical Detector of Ultrasound for Medical Imaging Applications
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Broadband Optical Activity Spectroscopy with Interferometric Fourier-Transform Balanced Detection.

Soumen Ghosh1, Georg Herink2, Antonio Perri1,3

  • 1Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano, Italy.

ACS Photonics
|September 3, 2021
PubMed
Summary

This study introduces a novel, simplified setup for broadband optical activity measurements, overcoming limitations of traditional spectropolarimeters. The technique enables rapid and sensitive characterization of chiroptical properties across a wide wavelength range.

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Area of Science:

  • Chiroptics
  • Spectroscopy
  • Nanophotonics

Background:

  • Optical activity measurements (circular dichroism, CD, and optical rotatory dispersion, ORD) are crucial for analyzing molecular and nanoplasmonic systems.
  • Conventional spectropolarimeters are bulky, slow, and limited to narrowband scanning, hindering broader application.
  • A need exists for faster, more versatile techniques to measure optical activity across broad spectral ranges.

Purpose of the Study:

  • To develop a simplified, broadband technique for measuring optical activity.
  • To overcome the limitations of conventional spectropolarimeters in terms of speed and spectral range.
  • To demonstrate the sensitivity and applicability of the new method for various analytical tasks.

Main Methods:

  • Combines balanced detection with interferometric Fourier-transform spectroscopy.
  • Utilizes a linearly polarized field and an orthogonally polarized chiral free-induction-decay field.
  • Employs a birefringent common-path interferometer for delay scanning and a balanced detector for polarization rotation measurement.

Main Results:

  • Simultaneous retrieval of broadband CD and ORD spectra via Fourier transform.
  • Achieves state-of-the-art sensitivity using an incoherent thermal light source.
  • Demonstrates sensitive glucose concentration measurements and real-time chemical reaction monitoring.

Conclusions:

  • The developed technique offers a simple, sensitive, and broadband approach to optical activity spectroscopy.
  • It significantly advances the study of chiroptical properties in diverse systems.
  • The setup is adaptable for transient spectroscopy and imaging, opening new research avenues.