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Acute cerebral microbleeds at the edge of lacunar strokes: cause or result

Keisuke Koizumi1, Hiromasa Sato1, Masahiro Ebitani1

  • 1Department of Neurology, 73464Aizawa Hospital, Aizawa Hospital, Japan.

The Neuroradiology Journal
|September 3, 2021
PubMed

Insights

Cerebral microbleeds may directly cause lacunar strokes by occluding small arteries. This finding suggests a novel pathogenic link between microbleeds and lacunar infarction in the basal ganglia.

Area of Science:

  • Neurology
  • Cerebrovascular Diseases
  • Neuroimaging

Background:

  • Lacunar strokes are small infarcts often affecting the basal ganglia.
  • The relationship between cerebral microbleeds and lacunar strokes remains incompletely understood.

Observation:

  • Two patients with basal ganglia lacunar strokes presented with co-occurring acute cerebral microbleeds.
  • Microbleeds were located near the infarction margins and appeared to be acutely developed based on surrounding edema.
  • These microbleed locations corresponded to potential occlusion sites of lenticulostriatal arteries.

Findings:

  • Cerebral microbleeds may precede and cause lacunar infarction through arterial occlusion.
  • This challenges the view of microbleeds as solely consequences or unrelated findings.

Implications:

  • Understanding this pathogenic mechanism can refine stroke diagnosis and treatment strategies.
  • Further research into microbleed-induced arterial occlusion is warranted for cerebrovascular disease management.
Keywords:
Cerebral microbleedMRIgradient-echo T2*-weighted MRI imagelacunar strokelenticulostriatal artery

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