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Pyogenic Granuloma of the Proximal Part of a Nail Unit in a Child
Ružica Jurakić Tončić1, Anamaria Balić, Danijela Ćurković
1Ružica Jurakić Tončić, MD, PhD, University of Zagreb School of Medicine, Department of Dermatology and Venereology, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia; rjtoncic@gmail.com.
Insights
This case report details a proximal pyogenic granuloma in a child, a rare but benign nail unit lesion. Excisional biopsy confirmed the diagnosis and successfully treated the painful, fast-growing tumor.
Area of Science:
- Dermatology
- Pediatric Surgery
- Oncology
Background:
- Pyogenic granuloma (PG) is a benign vascular proliferation that can occur in various locations.
- PGs of the nail unit are uncommon, often presenting as rapidly growing, painful lesions.
- Differential diagnosis for nail unit lesions includes aggressive tumors like amelanotic melanoma and squamous cell carcinoma (SCC).
Observation:
- A 4-year-old child presented with a painful, fast-growing lesion on the proximal nail unit.
- Clinical examination revealed an exophytic, partially exulcerated lesion with uneven coloration.
- Dermoscopy showed nonspecific vascular structures, hemorrhage, and a 'sticky fiber' sign.
Findings:
- Histopathological examination confirmed the diagnosis of pyogenic granuloma.
- The lesion was successfully treated with complete excisional biopsy, serving both diagnostic and therapeutic roles.
Implications:
- This case highlights that pyogenic granulomas, though rare, can occur in the pediatric nail unit.
- Prompt diagnosis and biopsy are crucial to rule out rare but aggressive malignancies in pediatric nail lesions.
- Excisional biopsy is an effective treatment for symptomatic and destructive pyogenic granulomas of the nail unit.
Abstract:
Dear Editor, We present a case of proximal pyogenic granuloma in 4-year-old child. The patient presented to our Department due to a fast-growing lesion on the proximal part of the nail unit. The lesion had appeared over several weeks, and it was extremely painful for the child. On the day of the 1st visit, the lesion was not bleeding but was very painful during examination and photo-documentation. Clinically, it presented as an exogenous tumoral lesion of the proximal 1/3 of the nail, partially exulcerated with one part exhibiting coagulated hemorrhage and with uneven coloration (Figure 1). The lesion was not sharply demarcated. Dermoscopically, the majority of the lesion presented an unspecific dermoscopic structure, orange background color, and matched the criteria for a vascular lesion: few unspecific vessels and hemorrhage. The "sticky fiber" sign was also present (Figure 2). Since the lesion was fast-growing and due to the unspecific dermoscopic appearance, the child was referred to a pediatric surgeon and a complete excisional biopsy of the lesion was performed. The dermoscopy of pyogenic granuloma has been already described (1). The histology report confirmed pyogenic granuloma. Pyogenic granulomas of the nail unit are not a common finding, but our case confirms that even this location can be site of this type of benign lesion. It more commonly found in the periungual region and can be expected due to adverse effects of different kinds of systemic therapies. However, due to differential diagnosis that includes different types of tumors occurring at the nail unit, most importantly amelanotic melanoma and SCC, it is suggested to excise or take a biopsy of this type of lesion to be able to exclude aggressive tumor types, which are very rare but not impossible the in pediatric population (2). In cases of unquestionable diagnosis, several local treatments are available. Since the lesion presented a destructive nature in our case, we decided to perform excisional biopsy followed by histology, which in our case was both a diagnostic and therapeutic procedure.
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