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Updated: Oct 21, 2025

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
[Guillian Barré syndromeafter mRNA-1273 vaccination against COVID-19]
Søren Kirchhoff Christensen, Martin Ballegaard, Magnus Spangsberg Boesen1
1magnus.spangsberg.boesen@regionh.dk.
Abstract:
Vaccination may on rare occasions trigger Guillian Barré syndrome, and the syndrome has previously been associated with vaccines against H1N1 swine flu. We present a case report of a 73-year-old man who received SARS-CoV-2 mRNA-1273-vaccine (Spikevax, Moderna Inc., MA, USA) and subsequently experienced diarrhoea, sensory ataxia, gait disorder, back pain, bilateral facial palsy, and dysarthria. A nerve conduction study was compatible with demyelinating polyneuropathy, and he was diagnosed with Guillian Barré syndrome. We discuss vaccines as triggers of Guillian Barré syndrome and recommendations for revaccination in these individuals.
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