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Updated: Oct 21, 2025

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Trend in stroke mortality in Chile from 1980 to 2015]
Álvaro Soto V1, Jairo Vanegas L2
1Departamento de Especialidades Médicas, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.
Stroke mortality in Chile significantly decreased between 1980 and 2015, with rates dropping from 92.8 to 34.4 per 100,000. This decline was more pronounced in women, indicating a positive public health trend.
Area of Science:
- Public Health
- Epidemiology
- Cardiovascular Disease Research
Background:
- Stroke is a leading cause of death in Chile, accounting for 7.3% of all fatalities in 2019.
- Recent decades have seen significant reductions in stroke mortality across Latin America.
Purpose of the Study:
- To analyze the temporal trends in stroke mortality in Chile.
- The study period spans from 1980 to 2015.
Main Methods:
- Utilized age-standardized death rate (ASDR) data for stroke mortality per 100,000 inhabitants.
- Employed joinpoint regression analysis to identify trends and calculate the average annual percent change (AAPC) by gender.
Main Results:
- Stroke ASDR declined from 92.8 per 100,000 in 1980 to 34.4 per 100,000 in 2015.
- The overall AAPC was -2.8%, with significant changes observed in 2008 and 2012.
- Women experienced a slightly greater AAPC (-2.9%) compared to men (-2.4%).
Conclusions:
- Stroke mortality rates in Chile demonstrated a significant decreasing trend from 1980 to 2015.
- The reduction in stroke mortality was particularly notable among women.
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