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Some properties of protein in synaptosomal fractions from El mouse cerebral cortices
S Yamagami1, D Furutsuka, K Mori
1Department of Neuropsychiatry, Osaka City University Medical School, Japan.
The Japanese Journal of Psychiatry and Neurology
|September 1, 1987
Abstract:
Synaptosomal and TCA insoluble proteins were prepared from the cerebral cortices of El(+) during the interictal periods, El(0) which did not stimulate and convulse at all, the seizure-nonsusceptible ddY mice. Both the proteins analyzed by SDS-PAGE electrophoresis indicated 5 major bands and 20-30 minor bands. In the major bands, 67K protein of the synaptosomal and TCA insoluble proteins in the El(+) mice was significantly lower than those of the ddY or El(0) mice and of the ddY mice, respectively.