Related Experiment Video
Updated: Oct 21, 2025
Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina
Published on: February 22, 2014
Acute macular neuroretinopathy following Pfizer-BioNTech COVID-19 vaccination
Daniel A Valenzuela1, Sylvia Groth1, Kenneth J Taubenslag1
1Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Purpose:
To describe a case of acute macular neuroretinopathy (AMN) in a patient immediately following administration of the Pfizer-BioNTech COVID-19 vaccine.
Observations:
The patient complained of paracentral scotoma supported by paracentral visual field loss on multiple Humphrey visual fields that corresponded to outer retinal pathology on optical coherence tomography. The patient's symptoms resolved without treatment.
Conclusions And Importance:
We conclude that the clinical testing demonstrated findings consistent with AMN. AMN may be an exceedingly rare adverse ocular effect of a novel vaccine and likely only in the setting of multiple other risk factors. Despite this, we strongly recommend vaccination against COVID-19.
