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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

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Non-parathyroid hypercalcemia during lactation: a case report.

Wei Shi¹, Xiajuan Wang¹, Jiayue Yang¹

¹Endocrine Department, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.

Annals of Palliative Medicine

|September 7, 2021

Summary

Non-parathyroid hypercalcemia during lactation is a rare emergency. Terminating lactation effectively treated a patient with hypercalcemia symptoms, normalizing serum calcium levels.

Keywords:

Hypercalcemia case report lactation parathyroid hormone (PTH)parathyroid hormone related peptide

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Area of Science:

Endocrinology
Nephrology
Obstetrics & Gynecology

Background:

Hypercalcemia is a critical condition with potentially fatal outcomes.
Non-parathyroid hypercalcemia involves calcium redistribution and suppressed parathyroid hormone (PTH) secretion.

Observation:

A 27-year-old lactating female presented with fatigue, anorexia, knee pain, and numbness.
Elevated serum calcium and decreased PTH levels confirmed hypercalcemia.
Symptoms developed during lactation, suggesting a potential link.

Findings:

The patient received calcitonin and underwent lactation termination.
Within two weeks, knee pain resolved and serum calcium normalized.
This case highlights a rare instance of non-parathyroid hypercalcemia during lactation.

Implications:

Lactation should be considered a potential cause of non-parathyroid hypercalcemia.
Lactation termination may be a viable treatment for hypercalcemia linked to excessive milk production.
Further research is warranted to understand the relationship between lactation and hypercalcemia.