Clinical Validation of Superficial Lip Injections Utilizing Cohesive Polydensified Matrix Hyaluronic Acid-Based Soft...

Area of Science:

• Dermatology
• Aesthetic Medicine
• Plastic Surgery

Background:

• Optimal injection techniques and dermal filler selection are crucial for natural and durable lip augmentation.
• Achieving improved lip architecture requires careful consideration of both technique and material.

Purpose of the Study:

• To evaluate the placement, tissue integration, and impact on lip shape of CPM-HA fillers after superficial lip injections.
• To assess the longevity and patient satisfaction with CPM-HA fillers in lip contouring and volumization.

Main Methods:

• Superficial direct tissue action technique with CPM-HA lip fillers, 30G needle, and retrograde microthreading.
• High-resolution ultrasound imaging, 3D surface scanning, and Global Aesthetic Improvement Scale (GAIS) assessments were used.
• Evaluations were conducted pre-injection and at 1, 3, and 6 months post-injection.

Main Results:

• Ultrasound showed temporary increased distance between skin and orbicularis oris muscle, indicating product integration by 3 months.
• Significant increases in total lip surface area, Cupid's bow distance, philtral height, and upper lip projection were observed at 3 months.
• Improved lip aesthetics and volume were maintained in 70% of patients up to 6 months, with increased dry mucosa thickness persisting.

Conclusions:

• Superficial injection of CPM-HA fillers is a safe and effective method for lip architecture and volume enhancement.
• The study demonstrated homogeneous dermal integration and sustained aesthetic outcomes for up to six months.
• CPM-HA fillers provide predictable and long-lasting results for lip augmentation procedures.