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In vitro investigations with selective adsorbents for IgE and IgM
1Department of Internal Medicine, Wilhelm-Pieck-University, Rostock, GDR.
Biomaterials, Artificial Cells, and Artificial Organs
|January 1, 1987
Abstract:
In vitro studies were carried out with IM-T. This adsorbent consists of polyvinyl alcohol joined with tryptophan side chains and was delivered by ASAHI Medical Co., Ltd., Tokyo/Japan. It was found that IM-T binds immunoglobulins G and M and also immune complexes only moderately but IgE was adsorbed in remarkable amounts. A clear dose-dependent was adsorbed in remarkable amounts. A clear dose-dependent manner of the IgE adsorption could be stated. Kinetic studies revealed that the binding was only slow and gradual.