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Updated: Oct 21, 2025

Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
Published on: February 23, 2024
Occlusal changes in orthodontically treated subjects 40 years after treatment and comparison with untreated control
Karina Maria Salvatore Freitas1, Camila Massaro2, Felicia Miranda2
1Department of Orthodontics, Uningá University Center, Maringá, Paraná, Brazil; Department of Orthodontics, Bauru Dental School, University of São Paulo, Bauru, São Paulo, Brazil.
Introduction:
The objective of this study was to compare the aging changes of the dental arches in orthodontically treated and untreated subjects after a 4-decade follow-up period.
Methods:
This retrospective study analyzed 2 groups. The treated group comprised 29 patients (11 male, 18 female) presenting with Class I or Class II malocclusions orthodontically treated with extractions of 4 first premolars. Dental models taken at pretreatment (12.84 years), posttreatment (14.95 years), and long-term posttreatment (51.37 years) were evaluated. The untreated (control) group consisted of 22 untreated patients with dental models taken at 13.32, 17.82, and 60.95 years of age. The dental models were digitized, and the following variables were evaluated: Little irregularity index, intercanine, interpremolar and intermolar widths, arch length, arch perimeter, overjet, and overbite. Interphase comparison of the treated group was performed with repeated measures analysis of variance and Tukey tests. Intergroup comparisons were performed using t tests (P <0.05).
Results:
Crowding was corrected with treatment but relapsed significantly in the long term. Intercanine width increased with treatment and decreased in the long term. Interpremolar and intermolar widths, arch perimeter, and length decreased with treatment and continued to decrease long-term posttreatment. Overjet and overbite were corrected with treatment and remained stable in the long term. From posttreatment to long-term posttreatment, a greater crowding increase was observed in the treated group than in the untreated group. The treated group demonstrated a greater decrease in mandibular intercanine and maxillary and mandibular interpremolar widths than the untreated sample. Overbite increased in the treated group and decreased in the untreated group. The multiple regression analysis showed that previous 4-premolar extractions orthodontic treatment is significantly associated with anterior crowding in the long term.
Conclusions:
In the long-term, the treated patients showed relapse of crowding and a decrease in arch form. Long-term changes of treated patients were different from untreated subjects. Relapse might have contributed to greater changes in incisor crowding and arch widths observed in the treated patients.
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