Related Experiment Video
Updated: Oct 21, 2025

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
Published on: November 11, 2022
Coronavirus disease 2019 pandemic and anxiety: a longitudinal study in 287 Brazilians
Andressa Caroline Martins de Souza1, Agnes Zanotto Manoel1, Poliana Zanotto Manoel1
1Faculdade Evangélica Mackenzie do Paraná - Curitiba (PR), Brazil.
Objective:
The aim was to study the prevalence of symptoms of anxiety and post-traumatic stress in a sample of Brazilians and their relationship with sex, age, and work situation, and compare if these symptoms change with 8 weeks of quarantine.
Methods:
Online survey to collect epidemiological data and apply the Beck Anxiety Inventory (BAI) and Impact of Event Scale-Revised (IES-R). Eight weeks later, the researchers requested the same requirements to complete the BAI and IES-R and compare the results.
Results:
The sample of 287 answered the first and second questionnaires, being 72.8% women, with a median age of 22 years. In the first interview, the median BAI was 12 (7-19) and the median IES-R was 27.0 (15-40); in the second, the median BAI was 11 (6-22) and the IES-R was 30 (15-41) with p<00001 and 0.09, respectively. Anxiety levels were worse in females (p<0.0001 for both BAI and IES-R) and in those who worked/studied in the area of health (p=0.001 for BAI and 0.01 for IES-R). There was a negative correlation between age and anxiety (p<0.0001 for BAI and IES-R).
Conclusions:
A high prevalence of anxiety that lowered after 8 weeks were found. Anxiety was worse in females, in younger people, and in those who worked/studied in the area of health.
Related Concept Videos
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Generalized Anxiety Disorder
Social Anxiety Disorder
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Longitudinal Studies
Long-term Depression
Calcium Ion Concentration Mechanism
If over...

