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Prediction of secondary structure of human haptoglobin
W Dobryszycka1, W Kubisa, Z Kubicz
1Department of Pharmaceutical Biochemistry, Medical Academy, Wroclaw, Poland.
Acta Biochimica Polonica
|January 1, 1987
Abstract:
Secondary structure of alpha (light) and beta (heavy) chains of human haptoglobin was proposed. The Chou-Fasman predictive method was used in conjunction with the hydrophobic character and hydropathy scale value assigned to each amino acid residue in the primary sequence of the protein. Moreover, by means of hydrophilicity values of amino acids, the location of antigenic determinants was predicted.