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Updated: Oct 20, 2025

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Published on: August 22, 2012
Hepatitis e prevalence, knowledge, and practice of preventive measures among secondary school adolescents in rural
Chioma Ngozichukwu Pauline Mbachu1, Joy Chinelo Ebenebe2, Henry Chima Okpara3
1Department of Paediatrics, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria. chiomambachupauline@gmail.com.
Background:
Currently, there is a paucity of data on the knowledge and practice of preventive measures for Hepatitis E infection in Nigerian populations. This study provided data on the prevalence, knowledge and practices of prevention in an adolescent population from Nigeria.
Methods:
This cross-sectional study was conducted over 3 months among rural Nigerian secondary school adolescents. An interviewer-based questionnaire was used to collect data on sociodemographic profile, knowledge, and practice of preventive measures for Hepatitis E infection. Blood samples collected from participants were analysed for Hepatitis E IgG using Elisa Kits (Sigma Diagnostics, USA). Data were analysed using SPSS software version 20.0. Tests of association were done with a level of significance set at 5%.
Results:
A total of 9 out of the 414 participants tested positive for Hepatitis E IgG antibodies giving a prevalence of 2.2%. Significant factors for Hepatitis E infection were male gender {P = 0.004} and school {P < 0.001, however logistic regression gave infinite value. Most participants (98.6%) had poor knowledge of Hepatitis E infection, 239(57.7%) had good preventive practices, while 175(42.3%) had average preventive practices.
Conclusion:
A low prevalence of HEV infection was recorded among study participants. There was poor knowledge of Hepatitis E, and association could not be established between HEV infection and individual preventive practices.
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