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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
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Methicillin-resistant Staphylococcus aureus in Nepal
Lok Bahadur Shrestha1, Gopiram Syangtan2, Ajaya Basnet2
1School of Medical Sciences and The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.
JNMA; Journal of the Nepal Medical Association
|September 11, 2021
Summary
Staphylococcus aureus is common in clinical samples in Nepal, with high rates of multi-drug resistance and methicillin-resistant Staphylococcus aureus (MRSA). Antimicrobial resistance surveillance is crucial to control superbug spread.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Staphylococcus aureus is a significant pathogen causing various infections, including endocarditis and skin infections.
- It is also a common commensal organism, complicating infection control efforts.
Purpose of the Study:
- To summarize the prevalence of Staphylococcus aureus in clinical samples.
- To estimate the proportion of methicillin-resistant Staphylococcus aureus (MRSA) and antimicrobial resistance patterns.
Main Methods:
- Minireview of clinical samples.
- Analysis of Staphylococcus aureus and MRSA prevalence.
- Assessment of antimicrobial resistance, including multi-drug resistance and inducible clindamycin resistance.
Main Results:
- Staphylococcus aureus prevalence in Nepalese clinical isolates is 34.5%.
- Multi-drug resistance averages 57.1% among Staphylococcus aureus isolates.
- Methicillin-resistant Staphylococcus aureus (MRSA) constitutes 41.7% of isolates, with 35% showing inducible clindamycin resistance.
Conclusions:
- High prevalence of Staphylococcus aureus and significant antimicrobial resistance, including MRSA, observed in Nepal.
- Urgent need for a robust antimicrobial resistance surveillance system.
- Mitigation strategies are essential to combat the spread of resistant organisms and superbugs like MRSA.
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