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Updated: Oct 20, 2025

A Murine Ommaya Xenograft Model to Study Direct-Targeted Therapy of Leptomeningeal Disease
Published on: January 29, 2021
Lymphomatoid granulomatosis of the central nervous system (CNS-LYG) posing a management challenge
Mohsin Soleja1, Jesse Manuel Jaso2, Weina Chen2
1Division of Hematologic Malignancies and Cellular Therapy, Department of Internal Medicine, Harold C. Simmons Comprehensive Cancer Center UT Southwestern Medical Center Dallas TX USA.
Abstract:
Isolated central nervous system lymphomatoid granulomatosis (CNS-LYG) can mimic aggressive glioblastomas. We describe a complex presentation of CNS-LYG coexisting with immune thrombocytopenia successfully managed with rituximab and ultra-low-dose radiation therapy.
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