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Updated: Oct 20, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Hyperspectral imaging and robust statistics in non-melanoma skin cancer analysis
Lloyd A Courtenay1, Diego González-Aguilera1, Susana Lagüela1
1Department of Cartographic and Terrain Engineering, Higher Polytechnic School of Ávila, University of Salamanca, Hornos Caleros 50, 05003 Ávila, Spain.
Abstract:
Non-Melanoma skin cancer is one of the most frequent types of cancer. Early detection is encouraged so as to ensure the best treatment, Hyperspectral imaging is a promising technique for non-invasive inspection of skin lesions, however, the optimal wavelengths for these purposes are yet to be conclusively determined. A visible-near infrared hyperspectral camera with an ad-hoc built platform was used for image acquisition in the present study. Robust statistical techniques were used to conclude an optimal range between 573.45 and 779.88 nm to distinguish between healthy and non-healthy skin. Wavelengths between 429.16 and 520.17 nm were additionally found to be optimal for the differentiation between cancer types.

