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Postoperative Use of Ketorolac Improves Pain Management and Decreases Narcotic Use Following Primary Cleft Palate

Samuel Dudley1,2, Matthew Spence1,2, Robert Frederick1,2

  • 112326University of Tennessee Health Science Center, Memphis, TN, USA.

The Cleft Palate-Craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
|September 13, 2021
PubMed

Insights

Ketorolac effectively reduced narcotic use and pain scores in pediatric cleft palate surgery patients. Postoperative bleeding was infrequent, indicating a favorable safety profile for ketorolac in this population.

Area of Science:

  • Pediatric Surgery
  • Pain Management
  • Pharmacology

Background:

  • Cleft palate repair is a common pediatric surgical procedure.
  • Effective pain management is crucial for optimal recovery.
  • Opioids are often used but carry risks of adverse events.

Purpose of the Study:

  • To evaluate the efficacy and safety of ketorolac for pain management after cleft palate surgery.
  • To compare ketorolac with traditional opioid analgesia.

Main Methods:

  • Retrospective analysis of 89 pediatric patients undergoing primary cleft palate surgery.
  • Comparison of outcomes between patients receiving ketorolac and those receiving opioids.
  • Assessment of pain using the Face, Legs, Activity, Cry, Consolability (FLACC) score and opioid consumption (morphine equivalent dose - MED).

Main Results:

  • Patients receiving ketorolac showed significantly lower MED and FLACC scores.
  • Length of stay (LOS) was also reduced in the ketorolac group.
  • One instance of postoperative bleeding occurred in the ketorolac group; bleeding was rare overall.

Conclusions:

  • Ketorolac significantly decreases narcotic requirements and pain scores (FLACC) in pediatric cleft palate surgery.
  • Ketorolac demonstrates a favorable safety profile with rare postoperative bleeding.
  • Ketorolac is an effective alternative for pain management in this patient population.
Abstract

Keywords:
drug usepalatoplastypediatricssurgical complications

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