Driving Forces and Routes for Aggregation-Induced Emission-Based Highly Luminescent Metal Nanocluster Assembly

The development of ultrasmall, luminescent metal nanoclusters (MNCs) with aggregation-induced emission (AIE) characteristics is a relatively new research area that has gained significant attention in various multidisciplinary applications such as optoelectronics, sensing, imaging, and therapy. The numerous scientific breakthroughs in the AIE field provide many tools that, if incorporated into MNCs design strategies, could help realize various new and exciting MNC-based avenues that maximize the utilization of the AIE phenomenon. Indeed, leveraging the aggregation strategies from the AIE community with the judicious use of various covalent and noncovalent interactions has been demonstrated to be effective for constructing several MNC-based hybrid assemblies with enhanced AIE characteristics. In this Perspective, we summarize the key driving forces and routes of MNC assembly together with their impact on deciphering the working mechanism behind the AIE process. These strategies can inspire the design of highly luminescent MNC-based hierarchical functional materials across multiple length scales.