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Characteristics and management of asymptomatic SARS-CoV-2 infections

Mine Durusu Tanriover1,2, Anahita Fathi3,4,5, Matthias Raspe6

  • 1Department of Internal Medicine, Division of General Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Journal of Basic and Clinical Physiology and Pharmacology
|September 13, 2021
PubMed

Insights

Asymptomatic COVID-19 cases transmit SARS-CoV-2, necessitating effective testing, tracing, and isolation. Vaccination is key to preventing asymptomatic infections and controlling the pandemic.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic has caused significant global morbidity and mortality.
  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) transmission occurs from asymptomatic individuals.
  • Asymptomatic infections present a challenge due to potential viral loads without clear symptoms.

Purpose of the Study:

  • To highlight the significance of asymptomatic SARS-CoV-2 infections in pandemic transmission.
  • To emphasize the need for effective diagnostic and management strategies for asymptomatic COVID-19.
  • To underscore the role of vaccination in preventing asymptomatic transmission.

Main Methods:

  • Review of early pandemic observations on SARS-CoV-2 transmission.
  • Analysis of viral load data in asymptomatic individuals.
  • Evaluation of public health strategies including testing, contact tracing, quarantine, and isolation.
  • Assessment of vaccination impact on asymptomatic infections.

Main Results:

  • Asymptomatic individuals harbor SARS-CoV-2 and contribute to virus spread.
  • No approved antiviral therapies exist for asymptomatic SARS-CoV-2 infection.
  • Home management requires monitoring for deterioration and adherence to infection control.
  • Vaccination is a critical factor in reducing asymptomatic infections and transmission.

Conclusions:

  • Effective diagnosis and management of asymptomatic COVID-19 are crucial for pandemic control.
  • Preventing asymptomatic SARS-CoV-2 spread is vital for breaking transmission chains.
  • Community vaccination plays a pivotal role in mitigating the pandemic's impact.

Keywords:
COVID-19SARS-CoV-2asymptomaticmanagementpandemic

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