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Published on: December 15, 2023
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[Current status of nucleic acid testing for hepatitis C].
1National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Summary
Nucleic acid testing is crucial for diagnosing Hepatitis C Virus (HCV) infection, guiding treatment, and informing follow-up strategies. This review examines the necessity and current status of HCV nucleic acid testing to aid China
Area of Science:
- Hepatology
- Infectious Diseases
- Molecular Diagnostics
Background:
- Hepatitis C Virus (HCV) infection poses a significant global health challenge.
- Accurate diagnosis is essential for effective patient management and public health strategies.
- Nucleic acid testing (NAT) is the established gold standard for HCV detection.
Purpose of the Study:
- To review the necessity and current status of HCV nucleic acid testing.
- To analyze domestic and international literature on HCV NAT.
- To provide evidence for policy formulation aimed at HCV elimination in China.
Main Methods:
- Comprehensive literature review of domestic and international studies.
- Analysis of the evolution and maturity of HCV nucleic acid detection technologies.
- Synthesis of data regarding the clinical significance of HCV NAT.
Main Results:
- Nucleic acid testing is indispensable for accurate HCV diagnosis.
- HCV NAT guides critical treatment decisions and follow-up care.
- Detection technologies for HCV have advanced significantly.
Conclusions:
- HCV nucleic acid testing is vital for guiding treatment and follow-up strategies.
- The review supports the critical role of NAT in China's HCV elimination efforts.
- Policy development should leverage the advancements in HCV NAT.

