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236
Polymeric Materials as Potential Inhibitors Against SARS-CoV-2
Yunusa Umar1, Sirhan Al-Batty1, Habibur Rahman2
1Department of Chemical and Process Engineering Technology, Jubail Industrial College, Jubail Industrial City, 31961 Saudi Arabia.
Journal of Polymers and the Environment
|September 14, 2021
Summary
This review explores the SARS-CoV-2 lifecycle and highlights polymers and nanoparticles as potential inhibitors and immunizations against coronaviruses. These materials show promise for developing new technologies in polymer and nanoscience for viral disease prevention.
Area of Science:
- Virology
- Polymer Science
- Nanoscience
Background:
- The SARS-CoV-2 pandemic necessitated global research into viral mechanisms and prevention.
- Limited therapeutic interventions underscore the need for effective preventive strategies and supportive treatments.
Purpose of the Study:
- To review the lifecycle of SARS-CoV-2 within human host cells.
- To discuss preventive strategies against SARS-CoV-2 infection.
- To highlight the antiviral potential of various synthetic and natural polymers and nanoparticles.
Main Methods:
- Literature review focusing on SARS-CoV-2.
- Analysis of epidemiological factors (e.g., basic reproduction number, case fatality rate, incubation period).
- Examination of antiviral activities of polymers (chitosan derivatives, dendrimers, cyclodextrin, carrageenans, polyethyleneimine) and nanoparticles.
Main Results:
- Polymers and nanoparticles exhibit significant antiviral activities against coronaviruses.
- Mechanisms of virus inhibition, detection, and diagnosis are presented.
- Polymeric materials and nanoparticles show potential as inhibitors and for immunization.
Conclusions:
- Polymeric materials and nanoparticles represent promising avenues for developing novel antiviral strategies against coronaviruses.
- Further research in polymer and nanoscience can lead to new technologies for combating viral diseases.
- These materials offer potential for both therapeutic inhibition and prophylactic immunization.
