Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatially Resolved Diffusion NMR for Structurally Heterogeneous Materials.

Analytical chemistry·2026
Same author

Lithium-selective supramolecular assembly and capture by tripeptide gelators.

Chemical science·2026
Same author

Shear-Induced Anisotropic Supramolecular Gel Noodles for Improved Cell Guidance in Polarized Tissue Engineering.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Modular salt-induced nanostructures formed by a functionalized dipeptide system.

Matter·2026
Same author

Tutorial: Machine-Learning-Based CREASE-2D Analysis of 2D SAXS Profiles to Characterize Anisotropic Nanostructures in Soft Materials.

ACS measurement science au·2026
Same author

Functionalized azobenzenes for micellar solar thermal energy storage as a next-generation MOST system.

Communications chemistry·2025

Related Experiment Video

Updated: Oct 20, 2025

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

13.6K

Controlling hydrogel properties by tuning non-covalent interactions in a charge complementary multicomponent system.

Santanu Panja1, Annela Seddon2,3, Dave J Adams1

  • 1School of Chemistry, University of Glasgow Glasgow G12 8QQ UK dave.adams@glasgow.ac.uk.

Chemical Science
|September 15, 2021
PubMed
Summary

Mixing two non-gelling amphiphiles creates novel hydrogels. This pH-triggered process allows tuning of material properties like gel strength and stability for advanced material applications.

More Related Videos

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
08:50

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications

Published on: August 4, 2017

7.0K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.3K

Related Experiment Videos

Last Updated: Oct 20, 2025

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

13.6K
Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
08:50

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications

Published on: August 4, 2017

7.0K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.3K

Area of Science:

  • Supramolecular chemistry
  • Materials science

Background:

  • Small molecule gelators offer a versatile platform for creating advanced materials.
  • Mixing individual non-gelling components can lead to emergent material properties.

Purpose of the Study:

  • To describe a novel pH-triggered hydrogelation process by mixing two non-gelling amphiphiles.
  • To demonstrate control over material properties through tuning intermolecular interactions.

Main Methods:

  • Utilizing pH changes to trigger hydrogelation of mixed amphiphiles.
  • Modulating the degree of ionization of components to influence intermolecular interactions.
  • Employing a preparative pathway to control self-assembly and material characteristics.

Main Results:

  • Successful formation of hydrogels from two non-gelling amphiphiles via pH triggering.
  • Demonstrated ability to tune gel strength, stiffness, and thermal stability.
  • Observed unusual shrinking and swelling behavior in the resulting hydrogels.

Conclusions:

  • Mixing non-gelling amphiphiles provides a powerful strategy for designing functional hydrogels.
  • pH control and preparative methods offer precise tuning of hydrogel properties.
  • The developed hydrogels exhibit unique characteristics suitable for diverse applications.