Related Experiment Video
Updated: Oct 20, 2025
09:14
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
2.5K
Major Bleeding Complications in COVID-19 Patients
Ignacio Boira1, Violeta Esteban1, Sandra Vañes1
1Pulmonology, Hospital Universitario San Juan Alicante, San Juan de Alicante, ESP.
Cureus
|September 15, 2021
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause bleeding complications. This study reports four cases of arterial bleeding in patients with severe SARS-CoV-2 pneumonia on therapeutic anticoagulation.
Area of Science:
- Medicine
- Infectious Diseases
- Hematology
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is linked to thrombotic events.
- Bleeding complications, though less common, can occur later in the disease course, especially with anticoagulation.
Observation:
- This article details four hospitalized patients with severe SARS-CoV-2 pneumonia.
- These patients experienced arterial bleeding while receiving therapeutic doses of low-molecular-weight heparin.
Findings:
- A notable complication observed was arterial bleeding in patients with severe SARS-CoV-2 pneumonia.
- Therapeutic anticoagulation with low-molecular-weight heparin was a factor in these bleeding events.
Implications:
- Clinicians should be vigilant for bleeding risks in SARS-CoV-2 patients on anticoagulation.
- Further research is needed to understand and manage bleeding complications in severe COVID-19.
Related Concept Videos
01:24Disorders of Hemostasis
1.4K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.4K
01:28Esophageal Varices-II: Clinical Features and Management
179
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
179
01:30Venous Thrombosis IV: Nursing Management
52
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
52
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
419
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
419
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
75
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
75
01:29Pulmonary Embolism I: Introduction
192
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
192