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A Rare Entity of Undifferentiated Pleomorphic Sarcoma of the Mandible - A Case Report
T S Archana1, Akshay Shetty2, Mohammed Imran2
1Department of Oral and Maxillofacial Surgery, AECS Maaruti College of Dental Sciences and Research Center, Bengaluru, Karnataka, India.
The Rationale:
Undifferentiated pleomorphic sarcoma originally known as malignant fibrous histiocytoma was declassified by the World Health Organization in 2002 as a formal diagnostic entity and renamed as an undifferentiated pleomorphic sarcoma. It accounts for <1% of malignant tumours of the long bone.
Patient Concerns:
A 33-year-old male patient reported with swelling and pain in the lower left posterior jaw region for 3 months with a history of fall on the floor 3 months back.
Diagnosis:
On examination, diffuse solitary swelling was present on the left lower third of the face and was diagnosed radiographically and histopathologically as undifferentiated pleomorphic sarcoma of the mandible.
Treatment And Outcomes:
Selective neck dissection, followed by reconstruction with fibula osteomyocutaneous flap and then referred for adjuvant radiotherapy.
Take-Away Lessons:
Vimentin staining plays a substantial role in the diagnosis of undifferentiated pleomorphic sarcoma. A long-term follow-up after treatment is required to increase the chances of disease-free survival for the patients.
