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Viviene K Nguyen1, Kevin G M Kou1

  • 1Department of Chemistry, University of California, Riverside, California 92521, USA. kevink@ucr.edu.

Organic & Biomolecular Chemistry
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Nucleic acid biosynthesis is a fundamental biochemical process that produces the purine and pyrimidine nucleotides essential for DNA and RNA synthesis. This pathway maintains a balanced nucleotide pool, preventing imbalances that could jeopardize genetic integrity and cellular function. Given the crucial role of nucleotides, their synthesis is tightly regulated to ensure proper cellular homeostasis.Purine BiosynthesisThe biosynthesis of purine nucleotides begins with ribose-5-phosphate, a...
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