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Updated: Oct 20, 2025

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
Published on: November 2, 2018
High-resolution mid-infrared optical coherence tomography with kHz line rate
Abstract:
We report on mid-infrared optical coherence tomography (OCT) at 4 µm based on collinear sum-frequency upconversion and promote the A-scan scan rate to 3 kHz. We demonstrate the increased imaging speed for two spectral realizations, one providing an axial resolution of 8.6 µm, and one providing a record axial resolution of 5.8 µm. Image performance is evaluated by sub-surface micro-mapping of a plastic glove and real-time monitoring of CO2 in parallel with OCT imaging.
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