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Related Experiment Videos

HOMED: a homologous sequence editor.

P A Stockwell1, G B Petersen

  • 1Department of Biochemistry, University of Otago, Dunedin, New Zealand.

Computer Applications in the Biosciences : CABIOS
|March 1, 1987
PubMed
Summary

HOMED software simplifies homologous sequence alignment and display, offering editing and database maintenance tools. This program aids researchers in managing and analyzing related genetic sequences efficiently.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Aligning and displaying homologous sequences is crucial but challenging in bioinformatics.
  • Existing tools may lack user-friendly interfaces or comprehensive functionalities for sequence management.

Purpose of the Study:

  • To introduce HOMED, a novel software tool designed for efficient homologous sequence alignment and display.
  • To provide a user-friendly platform for editing, listing, and maintaining sequence databases.

Main Methods:

  • HOMED utilizes a full-screen editor emulating common text editors (KED, EDT) for simplified user interaction.
  • The software is implemented modularly in Pascal for enhanced portability across systems.
  • It offers functions for various sequence listing formats and consensus sequence generation.

Main Results:

  • HOMED successfully enables parallel editing and listing of related sequences.
  • The software facilitates the generation of consensus sequences and provides database maintenance tools.
  • User learning is simplified through familiar text editor emulation.

Conclusions:

  • HOMED offers a practical and portable solution for homologous sequence alignment and management.
  • The software enhances efficiency and accessibility for researchers working with genetic sequence data.

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