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Complete surgical revascularization: Different definitions, same impact?
Paulo Veiga Oliveira1, Márcio Madeira1, Sara Ranchordás1
1Department of Cardiothoracic Surgery, Santa Cruz Hospital, Lisbon, Portugal.
Insights
Complete functional revascularization improves survival after coronary artery bypass grafting (CABG). This study highlights the need for a standardized definition to optimize patient outcomes in cardiac surgery.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Coronary Artery Bypass Grafting
Background:
- Inconsistent definitions of complete revascularization exist in coronary surgery literature.
- Lack of consensus on the definition of complete revascularization impacts patient outcomes.
- The study addresses the need for a standardized definition in cardiac surgery.
Purpose of the Study:
- To evaluate which definition of complete surgical revascularization correlates with early and late outcomes.
- To compare the impact of numerical, functional, anatomical conditional, and anatomical unconditional revascularization definitions.
- To identify predictors of mortality and revascularization needs post-CABG.
Main Methods:
- Retrospective analysis of 162 patients undergoing isolated CABG between 2012 and 2016.
- Patients were assessed for compliance with four different definitions of complete revascularization.
- Outcomes included Major Adverse Cardiac and Cerebrovascular Events (MACCE), survival, and repeat revascularization, with a median follow-up of 5.5 years.
Main Results:
- Complete functional revascularization was a significant predictor of increased survival (HR: 0.47; p=0.041).
- No other definitions of complete revascularization demonstrated an impact on follow-up mortality.
- Age and cardiac dysfunction were identified as predictors of long-term mortality.
Conclusions:
- A universally accepted definition for complete coronary revascularization is currently lacking.
- Functional revascularization appears to be a crucial factor for long-term survival post-CABG.
- The study emphasizes the importance of viability assessment in guiding CABG procedures.
Background:
There are several different definitions of complete revascularization on coronary surgery across the literature. Despite the importance of this definition, there is no agreement on which one has the most impact. The aim of this study was to evaluate which definition of complete surgical revascularization correlates with early and late outcomes.
Methods:
All consecutive patients submitted to isolated CABG from 2012 to 2016 with previous myocardial scintigraphy were evaluated.
Exclusion Criteria:
emergent procedures and previous cardiac surgery procedures. The population of 162 patients, follow-up complete in 100% patients; median 5.5; IQR: 4.4-6.9 years. Each and all of the 162 patients were classified as complying or not with the four different definitions: numerical, functional, anatomical conditional, and anatomical unconditional. Perioperative outcome: MACCE; long-term outcomes: survival and repeat revascularization. Univariable and multivariable analyses were developed to detect predictors of outcomes.
Results:
Complete functional revascularization was a predictor of increased survival (HR: 0.47; CI 95: 0.226-0.969; p = .041). No other definitions showed effect on follow-up mortality. Age and cardiac dysfunction increased long-term mortality. The definition of complete revascularization did not have an impact on MACCE or the need for revascularization CONCLUSIONS: A uniformly accepted definition of complete coronary revascularization is lacking. This study raises awareness about the importance of viability guidance for CABG.
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